Emergency Life Saving and Critical Care Drugs List of Nepal

Emergency Life Saving and Critical Care Drugs List of Nepal

The 4th amendment of Drug Registration Regulation-2038 on 2078 includes the following 191 Emergency, Life saving and Critical-care drugs. The number of drugs was increased to 191 with addition of 96 new drugs. The amendment also includes the list of drugs for treatment of orphan and neglected diseases.

List of Emergency, Life Saving and Critical Care Drugs in Nepal 2022

S.N	Name of Medicine	Dosage form and Strength
1.	Acetazolamide	Powder for injection 500 mg Tablet : 250 mg
2.	Acetylcysteine	Injection: 200 mg/ml in 10 ml ampoule Tablet (effervescent): 600 mg
3.	Acetylsalicylic Acid (aspirin)	Tablet: 50 mg, 75 mg, 150 mg, 300 mg
4.	Aciclovir	Powder for injection: 250 mg (as sodium salt) in vial, Tablet: 400 mg, 800mg, 500mg
5.	Adenosine	Injection: 3mg/ml in 2 ml vial
6.	Albumin, human	Injectable solution: 5%, 20%
7.	Alteplase (tissue plasminogen activator)	Injection: 20 mg, 50 mg in vial
8.	Amikacin	Injection: 250mg (as sulfate)/ml in 2 ml vial
9.	Aminophylline	Injection: 25 mg/ml
10.	Amiodarone	Injection: 50 mg (hydrochloride)/ ml in 3 ml ampoule
11.	Amlodipine	Tablet: 2.5 mg, 5 mg (as maleate, mesylate or besylate)
12.	Amoxicillin	Powder for injection: 250 mg, 500 mg, 1g (as sodium) in vial
13.	Amoxicillin + Clavulanic Acid	Powder for injection: mg (as sodium) + 200 mg (as potassium salt) in vial
14.	Amphotericin B	Powder for injection: 50 mg in vial (liposomal complex)
15.	Anti-D immunoglobulin	Injection: 250 mcg in single dose vial
16.	Anti-Rabies Hyperimmune Serum	Injection: 10000 IU in 5 ml ampoule
17.	Anti-Tetanus Immunoglobulin	Injection: 500 IU, 1000 IU/ml, 3000 IU/ml in vial
18.	Atorvastatin	Tablet: 80 mg
19.	Atropine	Eye drop: 1.00% Injection: 0.6 mg (as sulfate)/ml in 1 ampoule, 30 ml vial
20.	Benzathine Benzylpenicillin	Powder for injection: 60 000 IU, 1200 000 IU, 2400 000 IU
21.	Benzylpenicillin (penicillin G)	Powder for injection: 300 mg (=0.5 million IU), 600 mg (=1 million IU) (as sodium or potassium salt) in vial
22.	Budesonide	Metered dose inhaler (aerosol): 200 mcg per dose
23.	Bupivacaine	Injection: 0.25%, 0.5% (hydrochloride) in vial Injection for spinal anesthesia: 0.5% (hydrochloride) in 4 ml ampoule, mixed with 7.5% glucose solution
24.	Calcium Chloride	Injection: 100mg/ml
25.	Calcium Gluconate	Injection: 100 mg/ml in 10 ml ampoule
26.	Carboprost	Injection: 250 mcg
27.	Cefepime	Injection: 1gm/ml
28.	Cefotaxime	Powder for injection: 500 mg, 1g (as sodium salt) per vial
29.	Ceftazidime	Injection: 500 mg/ml
30.	Ceftriaxone	Powder for injection: 250 mg, 1 g (as sodium salt) in vial
31.	Charcoal, Activated	Powder: 10 g in sachet (oral liquid as sorbitol-based slurry)
32.	Chloramphenicol	Powder for injection: 1g (as sodium succinate) in vial
33.	Chlorpromazine	Injection: 25 mg (hydrochloride)/mi in 2 ml ampoule
34.	Ciprofloxacin	Injection: 200 mg per vial of 100 ml Topical: 0.30%
35.	Clonidine	Tablet (Immediate release): 100 mcg
36.	Clopidogrel	Tablet: 75 mg
37.	Compound solution of sodium lactate (Ringer’s lactate)	Injectable solution, in Plastic Bottle, Pouch
38.	Dantrolene	Powder for injection: 20 mg in vial
39.	Deferoxamine	Powder for injection: 500 mg (mesilate) in vial
40.	Desmopressin	Injection: 4mcg/ml in ampoule

41.	Dexamethasone	Injection: 4 mg (as disodium phosphate salt)/ml in 1 ml ampoule Tablet: 500 mcg, 4 mg
42.	Dexmedetomidine	Injection: 100 mcg/ml
43.	Diazepam	Injection; 5mg/ml in 2 ml ampoule (intravenous or rectal)
44.	Diclofenac sodium	Injection: 75 mg/ml
45.	Digoxin	Injection: 250 mcg/ml in 2 ml ampoule Oral liquid: 50 mcg/ml Tablet: 62.5 mcg, 250 mcg
46.	Digoxin immune fab	Powder for injection: 40 mg/vial (each 40 mg binds with 0.5 ml of digoxin)
47.	Diltiazem	Injection: 5mg/ml
48.	Dimercaprol (BAL)	Injection in oil: 50 mg/ ml in 2 ml ampoule
49.	Dinoprostone (Prostaglandin E2)	Topical: 2 mg
50.	Dobutamine	Injection: 12.5 mg (as hydrochloride)/ ml in 20 ml ampoule
51.	Dolutegravir	Tablet: 50 mg
52.	Dopamine	Injection: 40 mg (hydrochloride)/ml in 5 ml vial
53.	Doxycycline	Powder for injection: 100 mg in vial
54.	Dried Aluminum Hydroxide + Magnesium Hydroxide	Oral liquid: 250 mg/ 5ml + 250 mg/ 5 ml
55.	Drotaverine	Injection: 2% in vial
56.	Enalapril	Injection: 1.25 mg/ml Tablet: 2.5 mg
57.	Dnoxaparin	Injection: 20 mg/ 0.2 ml, 60 mg/0.6 ml, 80 mg/ 0.8 ml
58.	Dphedrine	Injection: 30 mg (hydrochloride)/ ml in 1 ml ampoule
59.	Dpinephrine (Adrenaline)	Injection: 1 mg (as hydrochloride or hydrogen tartarate) in 1 ml ampoule (1: 1000) Injection (pre-filled auto-injector): 1 mg/ml, 0.3 mg per dose (0.3ml)
60.	Dpinephrine Racemic (Adrenaline)	Injection: 2 mg (ass hydrochloride or hydrogen tartarate) in 1 ml ampoule (1:1000)

61.	Erythropoiesis- Stimulating Agents	Injection (pre-filled syringe) 1000IU/0.5ml; 2000IU/0.5 ml 3000IU/0.3ml; 4000IU/0.4 ml 5000IU/0.5ml; 6000IU/0.6 ml 8000IU/0.8ml; 10000IU/1ml 20000IU/0.5ml; 40000IU/1 ml
62.	Esmolol	Injection: 10 mg/ml
63.	Etophylline + Theophylline	Injection: 84.7 mg +25.3 mg/ml in 2 ml ampoule
64.	Fentanyl	Injection: 50 mcg/ml 2 ml ampoule/10 ml vial
65.	Filgrastim	Injection; 300 mcg/ 0.5 ml in prefilled syringe, 300 mcg/ml in 1 ml vial
66.	Fludrocortisone	Tablet: 100 mcg (acetate)
67.	Flumazenil	Injection: 100 mcg/ml solution in 5 ml, 10 ml ampoule
68.	Fluticasone	Metered dose inhaler (aerosol): 125 mcg and 250 mcg per dose
69.	Folinic acid (Leucovorin)	Injection: 10 mg/5ml
70.	Fomipezole	Injection: 5 mg (sulfate)/ ml in 20 ml ampoule
71.	Formoterol	Metered dose inhaler (aerosol): 12/ 20 mcg per dose
72.	Furosemide	Injection: 10 mg/ml in 2 ml ampoule
73.	Ganciclovir	Powder for injection: 500 mg in vial
74.	Gentamicin	Injection: 10 mg, 40 mg (as sulfate)/ ml in 2 ml vial
75.	Glucagon	Injection: 1 mg/ml
76.	Glucose with sodium chloride	Injectable solution: 5% glucose + 0.9% sodium chloride
77.	Glucose / dextrose	Injectable solution: 5% w/v isotonic, 25% w/v hypertonic, 50% w/v hypertonic
78.	Glyceryl trinitrate	Injection: 5 mg/ml
79.	Glycopyrrolate	Injection: 0.2 mg/ml in ampoule
80.	Haloperidol	Injection: 5 mg in 1 ml ampoule

81.	Heparin sodium (unfractionated)	Injection: 1000 IU/ml, 5000 IU/ml, 20000 IU/ml in 1 ml ampoule
82.	Hepatitis B	Vaccine
83.	Hepatitis B Immunoglobulin	Injection: 100 IU/ml
84.	Human Rabies Immunoglobulin	Injection: 1000 IU in 5 ml ampoule
85.	Hydralazine	Powder for injection: 20 mg (hydrochloride) in ampoule
86.	Hydrocortisone	Powder for injection: 100 mg (as sodium succinate) in vial with water for injection Tablet: 10 mg, 20 mg Injection (sodium succinate): 40 mg/ml in 5 ml vial
87.	Hyoscine Butylbromide	Injection: 20 mg/ml in 1 ml ampoule
88.	Insulin (soluble)	Injection: 40 IU/ml in 10 ml vial , 100 IU/ml in 10 ml vial
89.	Intralipid	Injectable solution: 20%
90.	Intraperitoneal dialysis solution	Parenteral solution
91.	Ipratropium bromide	Metered dose inhalation (aerosol): 20 mcg/dose Solution (inhalation) or respules: 250 mcg/ml
92.	Isoflurane	Inhalation
93.	Isoprenaline (isoproterenol)	Injection: 1 mg (hydrochloride)/ml in vial
94.	Isosorbide Dinitrate	Tablet (sublingual): 5mg, 10 mg
95.	Isosorbide Mononitrate	Tablet: 20 mg
96.	Ketamine	Injection: 50 mg (as hydrochloride)/ ml in 10 ml vial
97.	Ketorolac	Injection: 15 mg/ml
98.	Labetalol	Injection: 5mg/ml in 20 ml Tablet: 50 mg
99.	Lactulose	Oral liquid: 10 gm/15ml
100.	Lamivudine	Tablet:300 mg

101.	Levetiracetam	Injection: 100 mg/ml in 5 ml ampoule
102.	Levothyroxine	Tablet: 25 mcg, 50 mcg, 100 mcg ( sodium salt) Injection: 100 mcg per 5 ml (20 mcg per ml)
103.	Lidocaine ( Lignocaine preservative free)	Injection: 20 mg ( hydrochloride)/ml in vial
104.	Lidocaine ( lignocaine)	Injection: 1%, 2% ( hydrochloride) in vial Topical (sterile): 2% ( hydrochloride)
105.	Lidocaine ( lignocaine) + epinephrine( adrenaline)	Injection: 1%, 2% (hydrochloride sulfate)+ epinephrine 1: 200000 in vial
106.	Lithium carbonate	Solid oral dosage form: 300 mg ( sustained release)
107.	Lorazepam	Injection: 2 mg/ml in 1 ml ampoule
108.	Magnesium Sulfate	Injection: 500 mg/ml in 2 ml ampoule, in 10 ml ampoule
109.	Mannitol	Injectable solution: 20%
110.	Methyldopa	Tablet: 250 mg
111.	Methylergometrine (methergine)	Injection: 200 mcg (maleate)/ml in ampoule
112.	Methylprednisolone	Injection: 40 mg (as sodium succinate)/ml in 1 ml single vial: 80 mg (as sodium succinate)/ml in 1 ml single dose; Methylprednisolone 1000 mg powder
113.	Methylthioninium chloride (methylene blue)	Injection: 10 mg/ml in 10 ml ampoule
114.	Metoclopramide	Injection: 5 mg (hydrochloride)/ml in 2 ml ampoule
115.	Metoprolol	Injection: 1 mg/ml, Tablet: 12.5, 25, 50 mg Regular and Extended Release
116.	Metronidazole	Injection: 500 mg per vial of 100 ml
117.	Midazolam	Injection: 1 ml/mg in 5 ml multidose vial
118.	Mifepristone – misoprostol	Tablet (copackage)*: 200 mg Tablet: 200 mcg
119.	Misoprostol	Tablet: 200 mcg, 600 mcg Tablet (vaginal): 25 mcg
120.	Morphine	Injection: 10 mg (sulfate or hydrochloride) in 1 ml ampoule

121.	Multiple Electrolyte Solution / Balanced Electrolyte Solution	Multiple Electrolytes Injection: 140 mEq sodium, 5 mEq potassium, 3 mEq magnesium, 98 mEq chloride, 27 mEq acetate and 23 mEq gluconate in 1 liter.
122.	Naloxone	Injection: 400 mcg (hydrochloride) in 1 ml ampoule
123.	Neostigmine	Injection: 500 mcg in 1 ml ampoule, 2.5 mg (metilsulfate) in 1 ml ampoule
124.	Nifedipine	Capsule (immediate release): 10 mg
125.	Nimodipine	Tablet: 30 mg
126.	Norepinephrine (noradrenaline)	Injection: 1 mg/ml in 2 ml ampoule
127.	Normal Immunoglobulin (IvIg)	Intramuscular administration: 16% protein solution Intravenous administration: 5%, 10% protein solution Subcutaneous administration: 15%, 16% protein solution
128.	Octreotide	Injectable solution; 100 mcg/ml
129.	Ondansetron	Injection: 2 mg (as hydrochloride)/ml in 2 ml, 4 ml vial
130.	Oral Rehydration Salts	ORS Powder for dilution in 1 L (as per WHO recommended formula)
131.	Oseltamivir	Capsule: 30 mg, 45 mg, 75 mg (as phosphate)
132.	Oxygen	Inhalation
133.	Oxytocin	Injection: 5 IU/ml, 10 IU/ml in 1 ml ampoule
134.	Pantoprazole	Powder for injection: 40 mg in vial
135.	Paracetamol	Injection: 150 mg/ml in 2 ml ampoule, 10 mg/ml in 100 ml bottle (1gm/100ml) Suppository: 125 mg, 250 mg
136.	Pethidine	Injection: 50 mg (hydrochloride) in 1 ml ampoule
137.	Pheniramine	Injection: 22.75 mg (maleate)/ml
138.	Phenobarbital	Injection: 200 mg (sodium)/ml
139.	Phenylephrine	Injection: 10 mg/ml
140.	Phenytoin	Injection: 50 mg (sodium salt)/ml in 5 ml vial

141.	Physostigmine	Injection: 1 mg/ml
142.	Phytomenadione	Injection; 10 mg/ml
143.	Polygeline	Injectable solution: 3.5%
144.	Poly Venom Anti-Snake Serum	Injection in vial
145.	Potassium chloride	Injection: 15% in 20 ml ampoule
146.	Potassium ferric hexacyanoferrate (ii).2H2O (prussian blue)	Powder for oral administration
147.	Pralidoxime	Injection: 500 mg, 1 g (mesilate, chloride or iodide) in ampoule
148.	Procainamide	Injection: 100 mg/ml in 10 ml ampoule
149.	Procaine Benzylpenicillin	Powder for injection: 300 000 IU in vial
150.	Prochlorperazine	Injection: 12.5 mg/ml
151.	Promethazine	Injection: 25 mg (hydrochloride)/ ml in 2 ml ampoule
152.	Propofol	Injection: 10 mg/ml, 20 mg/ml
153.	Propranolol	Injection: 1 mg/ml
154.	Propylthiouracil	Tablet: 50mg
155.	Protamine Sulfate	Injection: 10mg/ml in 5 ml ampoule
156.	Pyridoxine	Tablet: 25 mg (hydrochloride)
157.	Rabies vaccine	Vaccine
158.	Ranitidine	Injection: 25 mg (as hydrochloride)/ ml in 2 ml ampoule
159.	Rasburicase	Powder and solvent for concentrate for solution for injection: 1.5 mg/ml
160.	Rocuronium	Injection: 10 mg/ml in 5 ml vial

161.	Salbutamol	Inhalation: 100 mcg/dose Injection: 50 mcg/ml in 5 ml ampoule Metered dose inhaler (aerosol)/ Rotahaler: 200 mcg (as sulfate) per dose
162.	Sodium Bicarbonate (sodium hydrogen carbonate)	Injectable solution: 7.5% solution in 10 ml ampoule
163.	Sodium chloride	Injectable solution: 0.9% (normal saline), 3% in 100 ml
164.	Sodium Nitrite	Injection: 30 mg/ml in 10 ml ampoule
165.	Sodium Nitroprusside	Powder for infusion: 50 mg in ampoule
166.	Sodium phosphate	Injection: 45 mmol/15 ml
167.	Sodium Polystyrene Sulfonate	Powder for oral solution: 15 g sachet
168.	Sodium Tetradecyl Sulfate	Injection: 3%, 1%, 0.5%
169.	Sotalol	Injection: 15 mg/ml
170.	Streptokinase	Injection: 750 000 IU, 1 500 000 IU in vial
171.	Surfactant (as beractant)	Suspension for intratracheal instillation: 25 mg/ml
172.	Suxamethonium (succinylcholine)	Injection: 50 mg (chloride)/ml in 10 vial
173.	Tenecteplase	Powder for injection: 40 mg (8,000 units) in a vial
174.	Tenofovir	Tablet: 300 mg
175.	Terbutaline	Injection: 1 mg/ml
176.	Terlipressin	Injection: 100 mcg/ml
177.	Tetanus Antitoxin	Injection: 1000 IU/ml, 3000 IU/ml in vial
178.	Tetanus Toxoid	Vaccine
179.	Thiamine	Injection: 100 mg/ml in 2 ml ampoule
180.	Thiopentone	Powder for injection: 500 mg
181.	Timolol	Eye drop: 0.50%
182.	Torsemide	Injection: 10 mg/ml in 2 ml
183.	Tramadol	Injection: 50 mg/ml
184.	Tranexamic Acid	Injection: 100mg/ml in 5 ml ampoule
185.	Valproic acid (sodium valproate)	Injection: 100 mg/ml in 4 ml ampoule; 100 mg/ml in 10 ml ampoule
186.	Vasopressin	Injection: 20 IU/ml in ampoule
187.	Vecuronium	Powder for injection: 4 mg, 10 mg (bromide) in vial
188.	Verapamil	Injection: 2.5 mg/ml in 2 ml ampoule
189	Voriconazole	Powder for injection: 200 mg in vial
190.	Warfarin	Tablet: 1mg, 2mg, 5 mg (sodium salt)
191.	Water for injection	Injection: 5 ml, 10 ml ampoule