Nepal Pharmacy Council License Exam Questions

Nepal Pharmacy Council License Exam Model Questions for Diploma Pharmacy and Bachelor of Pharmacy.

1. Issuance of identity card while deputing the Inspector is under…….. schedule of Drug Investigation and Inspection Rules, 2040 ?
a. Schedule1
b. Schedule 2
c. Schedule 3
d. Schedule 4

2. Mechanism of resistane to penicillins via beta lactamase is:
a. Altered penicilin binding protiens
b. Drug efflux
c. Breaks drug structure
d. Alteration in 50s ribosome structure

3. Which one is source of Anthraquinone?
a. Rhubarb
b. Senna
c. Valerin
d. Capsicum

4.The hormone responsible for “Flight and Fight” response is:
a. Adrenaline
b. Thyroxine
c. ADH
d. Oxytocin

5. The UV visible in the electromagnetic spectrum of radiant is
a. 200-400
b. 300-600
c. 400-800
d. 200-800

6.. Following are the barriers of effective communication except.
a. Environmnet
b. Time
c. Law regarding pharmacy practice
d. Pharmacist

7. The amount of sodium chloride in 540 ml of 0.9%W/V sodium chloride solution is…..
a. 4.86g
b. 48.6g
c. 0.486g
d. 2.5g

8. The investigator under the offences under Drug Act is
a. Police Inspector
b. Public Prosecutor
c. Drug Inspector
d. Director General of DDA

9. Which of the following does not fall under essential medicine list of Nepal?
a. Paracetamol
b. Ibuprofen + Paracetamol combination
c. Amoxicillin
d. Insulin

10. Alkaline diuresis is done for treatment of poisoning due to:
a. Morphine
b. Amphetamine
c. Phenobarbitone
d. Atropine

11. Low Vd means
a. The drug has low life
b. The drug dosent accumulate in tissues
c. The drug has low bioavailabilty
d. The drug has weak plasma protien binding

12. Which base is obtained from wool of ship
a. Lanolin
b. Yellow Petrolatum
c. Petrolatum
d. Liquid petrolatum

13. Which of the following is used as mucoadhesive
a. Acacia
b. Sodium CMC
c. Burnt sugar
d. Saccharin

14. Some crystalline substance liberates water of crystallization wholly or partly on exposure to humid atmosphere or during trituration and thus becomes wet and liquefy, are known as
a. Efflorescent
b. Delinquent
c. Hygroscopic
d. None

15. The provision of section 27 of drugs Act, 2035 is
a. Trademark
b. Prescribing rights
c. Clinical trial
d. Prohibition of drugs

16. The estimated minimum adult daily requirement of riboflavin is 10mg. what number of tablet should be advised for daily therapeutic dose if the capsule contains 2.5mg?
a. One BD
b. Three BD
c. Two BD
d. One in morning and 2 in evening

17. What is bincard used in store management?
a. Purchase card
b. Stock record card
c. Damage record card
d. Storage card

18. In normal phase elution of stationary phase is….and mobile phase is….
a. Aqueous, organic
b. Both aqueous
c. Both organic
d. Organic, Aqueous

19. The useful variable from in vitro dissolution test data for IVIVC includes:
a. Sampling interval
b. Sample volume
c. Volume of dissolution fluid
d. None

20. If the Carr’s index of a powder is 10% then the type of poder flow is
a. Poor
b. Excellent
c. Very poor
d. Good

21. Aconitine belongs to the group of ………
a. Steroidal Alkaloids
b. Terponoid Alkaloids
c. Indole Alkaloids
d. Quinolone Alkaloids

22. The most efficient heat exchange between the particles and flowing air occurs in the
a. Tray dryer
b. Spray dryer
c. Fludized bed dryer
d. Rotary dryer

23. Which of the following ACE inhibitor is not a prodrug
a. Fosinopril
b. Enalapril
c. Ramipril
d. Lisinopril

24. All of the following adverse effects are associayted with carbamezapine except:
a. Teratogenecity
b. Neurotoxicity
c. Decrease in antidiuretic hormone
d. Hypersensitivity

25. Dose of Vitamin K in serious bleeding is
a. 2.5mg
b. 5 mg
c. 10 mg
d. 20 mg

26. Which of the following is pH sensitive bioreodible polymer
a. Polymethacrylate
b. HPMC
c. NaCMC
d. None

27. Lactose is most widley used in dilunets in the tablet formulation. However it is not used in one of the following
a. Pyrazinamide
b. Ibuprofen
c. Sulfacetamide
d. Isoniazide

28. Titanium dioxide is commonly present in:
a. Vanishing cream
b. Sunscreen
c. Aqueous calamine cream
d. Opthalmic cream

29. The incubation period for sterility testing is?
a. 7 days
b. 10 days
c. 14 days
d. 21 days

30. Steam distillation is used to isolate
a. Volatile oil
b. Fixed oil
c. Alkaloid
d. Gkycoside

31. Which of the following vitamin is fat soluble?
a. Vitamin A
b. Vitamin C
c. Vitamin B2
d. Bitamin B1

32. What weight of a 5% (w/w) solution can be prepared from 2g of active ingredient?
a. 5gm
b. 10gm
c. 40gm
d. 50gm

33. The bodies which advice Government of Nepal on the basic principles and administrative matters relating to drug is:
a. DDA
b. DCC
c. NPC
d. NML

34. Which one of the following is not correct for penetration of drug into brain
a. Lipid solubility
b. Polarity of drug
c. Size of molecule
d. pH of drug

35. Mayers reagent contains
a. Potassium bismuth iodide
b. Saturated solution of picric acid
c. Potassium mercuric iodide solution
d. Aquoes iodine solution

36. Sink condition is related to
a. In vitro evaluation
b. In vivo evaluation
c. Sink condiotion
d. All

37. Equipment used in manufacture of ointments
a. Roller mill
b. Chilsoniator
c. Grinder mill
d. Planetary mixer

38. Which of the following doesn’t need disintegrating agent?
a. Enteric costed tablets
b. Sugar coated tablets
c. Effervescent tablets
d. Compression coated tablets

39. Following indicates prsence of free acid only in the fat/oil
a. Hydroxyl value
b. Sapnification value
c. Acid value
d. Iodine value

40. Spirinolactone is a prodrug and its metabolite is
a. Desmethyl spirinolactone
b. Canrencne
c. Acetylspirinolactone
d. None

41. The accumulation of follwing in the lens produces cataracts in diabetic patients:
a. Glucose
b. Galactose
c. Galacitol
d. Sorbitol

42. Lactulose is a
a. Osmotic laxative
b. Bulk laxative
c. Faecal softener
d. Stimulant purgative

43. Geriatric polpulation should be included in the following phase of clinical trials:
a. Phase I
b. Phase II
c. Phase III
d. Phase IV

44. Rabies vaccine is prepared using
a. Sheep blood
b. Mice lymph
c. Horse plasma
d. Fertile eggs

45. Which type of trichome is present in aswagandha?
a. Branched
b. Lignified
c. Glandular
d. None

46. TMS is used as a refernce compund for
a. NMR
b. IR
c. Mass
d. UV

47. The authority for banning of drugs is with
a. GoN
b. Ministry of heath
c. DDA
d. NPC

48. The concentration of magnesium sterates tablet granules lubricant is
a. 0.1-0.2T
b. 1.0-2.0%
c. 0.25-2.0%
d. 2.0-5.0%

49. Neomycn is obrained from
a. E.coli
b. S.aeruginosa
c. B.subtilis
d. S.fradiae

50. Which drug having side effect Reye’s syndrome ?
a. Rifampicin
b. Vancomycin
c. Aspirin
d. Tetracycline

51. Concentration of sodium benzoate as preservatives in parentrak products is
a. 0.02%
b. 0.5%
c. 0.1%
d. 0.03%

52. Ampoule packaging is example of……..
a. Primary packaging
b. Secondary packaging
c. Tertiary packaging
d. None

53. Devil’s dung synonyms of plant
a. Ephedra
b. Senna
c. Digitalis
d. Asafoetida

54. Which is example of Stimulant laxative?
a. Lactulose
b. Senna
c. Liquid Paraffin
d. Mannitol

55. Which is example of monoterpenes?
a. Lycopene
b. Santalol
c. Menthol
d. Squalene

56. Person shall make an application to the Department in the format as referred to in Schedule ………………… for To obtain certificate of registration of name, and shop or firm selling and distributing drug
a. Schedule 5
b. Schedule 7
c. Schedule 8
d. Schedule 9

57. In O/W type emulsion ………….. is dispersed phase
a. Water
b. Oil
c. Both
d. None

58. Moisture content in hard gelatin capsule is
a. 5%
b. 13-16%
c. 25%
d. 2%

59. Which is not sulphonamide?
a. Trimethoprim
b. Silver sulphadizine
c. Sulphamethoxazole
d. Suphasalazine

60. Sucarlfate should taken ……
a. Empty stomach
b. With meal
c. With PPI
d. With Milk

61. Opthalmic solution should be
a. Hypotonic
b. Hypertonic
c. Isotonic
d. Alkaline

62. Ergometrine is obtained from
a. Actinomyceties
b. Higher plant
c. Fungus
d. Synthesis

63. Which is the test of alkaloids in plant?
a. Molisch test
b. Mayer’s reagent
c. Saponification test
d. Legal test

64. What is the mamximum weight deviation limit as per IP for 50mg tablet?
a. 5%
b. 7.5%
c. 10%
d. 15%

65. Institute of Medicine, TU started Intermediate Pharmacy in the year.
a. 1997 AD
b. 1972 AD
c. 1986 AD
d. 1990 AD

66. The suitable packaging for codeine phosphate tablet is:
a. Aluminum – Aluminium Packing
b. Blister Packing using PVC
c. Blister Packing using PVDC
d. PVC- Aluminium Packing

67. Which alkaloid is volatile?
a. Narcotine
b. Papaverine
c. Nicotine
d. Thebaine

68. Allium sativum is used for the treatment of
a. Constpation
b. Rheumatic disease
c. Cancer
d. Asthma

69. Which is antidote of Heparin poisoning
a. Warfarin
b. Naloxone
c. Flumazenil
d. Protamine sulphate

70. The action based error is also called as,
a. Lapse
b. Slips
c. Exhaustion
d. Application

71. Which body suggest government on technical matters ?
a. DDA
b. DAC
c. DCC
d. NPC

72. Recognition of various pharmacopeias are illustrates under which schedule as per Drug Standard Regulation?
a. Schedule 1
b. Schedule 2
c. Schedule 4
d. Schedule 5

73. Who is eligible to be an investigation officer as per Narcotic Drug Control Act 2033:
a. At least sub- inspector of police or section officer
b. At least inspector of police or kharidar
c. At least sub- inspector of police of kharidar
d. Public prosecutor

74. Which raw material used for preparing Vegetarian Capsule
a. HPMC
b. Gelatin
c. Collagen
d. None of above

75. Chief constituent in coriander is?
a. Reserpine
b. Linalool
c. Camphor
d. Borneol

76. Sinigrin is example of glycoside?
a. O-glycoside
b. S-glycoside
c. N-glycoside
d. C-glycoside

77. Which of these drugs is known to cause brown-pink skin discoloration?
a. Griseofulvin
b. Dutasteride
c. Clofazimine
d. Clomifene

78. Purple glove syndrome is a side effect of which of these drugs?
a. Phenytoin
b. Digoxin
c. Chloramphenicol
d. Vancomycin

79. What is the strongest antibiotic for MRSA?
a. Amoxicillin
b. Ciprofloxacin
c. Vancomycin
d. Azithromycin

80. Which antibiotics in binds with 50S ribosomes?
a. Aminoglycosides
b. Tetracyclines
c. Penicillin
d. Chlormphenicol

81. Which pregency category medicine is safe in pregency
a. Category A
b. Category B
c. Category X
d. Category D

82. Idiosyncratic is ………….. type of reaction ?
a. Type A
b. Type B
c. Type C
d. Type D

83. Adulterants of rauwolfia serpentine are distinguished on the basis of
a. Presence of sclernchyma
b. Absence of sclerenchyma
c. Presence of parenchyma
d. Absence of parenchyma

84. Biological source for Isapgol:
a. Plantago ovata
b. Aegle marmelos
c. Giladinium amansii
d. Condrus cripsus

85. Reserpine is derived from-
a. Squalene
b. Homoserine
c. Tryptophan and tryptamine
d. Asparagines

86. Which of the following is a buffer solution?
a. H2SO4+CuSO4
b. CH3COOH + CH3COONH4
c. NaCl + NaOH
d. CH3COONa +CH3COOH

87. What is the principal of TLC?
a. Partition
b. Absorption
c. Adsorption
d. Both a and b

88. Pilocarpine is used for:
a. Glaucoma
b. Paralytic ileus
C. Urinary retention
d. All of the above

89. Dissociative anesthesia is produced by:
a. Ketamine
b. Fentanyl
C. Propofol
d. Both A and B are correct

90. Spironolactone can be usefully combine with the following diuretics except:
a. Furosemide
b. Amiloride
C. Hydrochlorthiazide
d. Chlorthalidone

91. Absorbable suture material among the following is.
a. Polypropamide
b. Nylon
c. Catgut
d. Silk

92. Hospital acquired infectious are called.
a. Primary infection
b. Secondary infection
c. Nosocomial infection
d. Latent infection

93. The colour of the container used for the disposal of waste sharps is.
A. Blue
B. Red
C. Yellow
D. Black

94. Which One of the following is NOT a salient feature of a Hospital Pharmacy?
a. Supply and storage of ancillary products
b. Design of a new drug
c. Supply of Pharmaceutical Drugs
d. Dispensing Of Narcotic Products

95. Which of the following phases is known as post marketing surveillance
A. Phase-1 trials
B. Phase-2 trials
C. Phase –3 trials
D. Phase-4 trials

96. What do you mean by medium hospital
a. 100 beds
b. 100-500 beds
c. More than 500 beds
d. All of above

97. Which semi synthetic penicillins is acid resistant
a. Phenoxymethyl penicillin
b. Methicillin
c. Amoxicillin
d. Piperacillin

98. Who is the chairman of DCC?
a. Minister of MOHP
b. Secretary of MOHP
c. DG of DDA
d. Pharmacist nominated by DDA

99. In prescription e.m.p. means
a. At bed time
b. Ointment
c. As directed
d. Drop

100. Which is main part of prescription
a. Superscription
b. Inscription
c. Signatura
d. Subscription