Pharmaceutical Analysis MCQs for Pharmacy License and Loksewa Exams
Preparing for the Nepal Pharmacy Council License Exam or Loksewa (Public Service Commission) Pharmacy Exams requires a strong grasp of pharmaceutical concepts, especially Pharmaceutical Analysis. This subject is a cornerstone of pharmacy practice, as it covers essential analytical skills like titrations, indicators, and modern instrumentation techniques used to ensure drug quality, purity, and safety.
To help students and professionals master this important subject, Pharma Info Nepal has compiled 30 multiple-choice questions (MCQs) based on key exam topics. These MCQs are designed to test your understanding of fundamental principles, practical applications, and analytical methods in pharmacy. Whether you’re revising for your upcoming license exam or strengthening your Loksewa preparation, this resource will give you a focused and effective study guide.
Stay tuned for more pharmacy exam resources, detailed explanations, and expert guidance from Nabin’s Pharma Classes – your trusted partner in building a strong pharmacy career.
Pharmaceutical Analysis MCQs
- Which of the following is a primary standard substance?
a) Sodium hydroxide
b) Potassium hydrogen phthalate (KHP)
c) Hydrochloric acid
d) Sodium carbonate (Na₂CO₃)
Answer: b) Potassium hydrogen phthalate (KHP) - The normality of a solution is defined as:
a) Moles of solute per liter of solution
b) Grams of solute per liter of solution
c) Gram equivalents of solute per liter of solution
d) Moles of solute per kilogram of solvent
Answer: c) Gram equivalents of solute per liter of solution - In a non-aqueous titration, glacial acetic acid is commonly used as:
a) Base
b) Acidic solvent
c) Oxidizing agent
d) Indicator
Answer: b) Acidic solvent - The indicator used in argentometric titration is:
a) Phenolphthalein
b) Methyl orange
c) Potassium chromate
d) Thymol blue
Answer: c) Potassium chromate - In complexometric titration, EDTA is used as:
a) Oxidizing agent
b) Reducing agent
c) Chelating agent
d) Primary standard
Answer: c) Chelating agent - In potentiometric titration, the endpoint is determined by:
a) Change in conductivity
b) Change in pH or potential
c) Color change of indicator
d) Formation of precipitate
Answer: b) Change in pH or potential - Which titration is suitable for assay of sodium chloride?
a) Acid-base titration
b) Precipitation titration
c) Redox titration
d) Complexometric titration
Answer: b) Precipitation titration - The titration method used to determine ascorbic acid content is:
a) Iodimetry
b) Argentometry
c) EDTA titration
d) Alkalimetry
Answer: a) Iodimetry - In redox titration, potassium permanganate acts as:
a) Reducing agent
b) Oxidizing agent
c) Chelating agent
d) Precipitating agent
Answer: b) Oxidizing agent - Back titration is used when:
a) Endpoint is not sharp
b) Sample is insoluble in solvent
c) Sample reacts slowly
d) All of the above
Answer: d) All of the above - Phenolphthalein is colorless in:
a) Acidic medium
b) Neutral medium
c) Alkaline medium
d) All of the above
Answer: a) Acidic medium - The pH range of methyl orange is:
a) 3.1–4.4
b) 4.0–6.5
c) 6.0–7.5
d) 8.0–9.8
Answer: a) 3.1–4.4 - A suitable indicator for titration of a strong acid with a weak base is:
a) Phenolphthalein
b) Methyl orange
c) Bromothymol blue
d) Cresol red
Answer: b) Methyl orange - The theory that explains indicator color change is:
a) Ostwald’s theory
b) Nernst equation
c) Gibbs adsorption theory
d) Kohlrausch’s law
Answer: a) Ostwald’s theory - The color change of phenolphthalein is due to:
a) Redox reaction
b) Structural change in ionized form
c) Formation of chelates
d) Formation of precipitate
Answer: b) Structural change in ionized form - The indicator used in iodometric titration is:
a) Starch
b) Methyl orange
c) Phenolphthalein
d) Ferroin
Answer: a) Starch - The suitable indicator for weak acid-strong base titration is:
a) Methyl orange
b) Phenolphthalein
c) Congo red
d) Methyl red
Answer: b) Phenolphthalein - In a redox titration using potassium dichromate, the external indicator used is:
a) Diphenylamine
b) Phenolphthalein
c) Bromocresol green
d) Congo red
Answer: a) Diphenylamine - An example of adsorption indicator is:
a) Starch
b) Potassium chromate
c) Fluorescein
d) Methyl orange
Answer: c) Fluorescein - Internal indicators are added:
a) To the standard solution
b) To the sample solution
c) To both solutions
d) Separately after titration
Answer: b) To the sample solution - The principle of UV-Visible spectroscopy is:
a) Absorption of infrared radiation
b) Absorption of UV/visible radiation
c) Emission of X-rays
d) Diffraction of light
Answer: b) Absorption of UV/visible radiation - The Beer-Lambert law relates absorbance with:
a) Concentration and wavelength
b) Concentration and path length
c) Concentration and temperature
d) Concentration and solvent polarity
Answer: b) Concentration and path length - In infrared spectroscopy, the fingerprint region is:
a) 4000–2500 cm⁻¹
b) 2500–1500 cm⁻¹
c) 1500–400 cm⁻¹
d) 5000–4000 cm⁻¹
Answer: c) 1500–400 cm⁻¹ - The detector used in flame photometry is:
a) Photodiode
b) Photoelectric cell
c) Thermocouple
d) Flame ionization detector
Answer: b) Photoelectric cell - The separation principle of HPLC is based on:
a) Mass-to-charge ratio
b) Partition coefficient
c) Thermal conductivity
d) Sedimentation rate
Answer: b) Partition coefficient - A polarograph is used to measure:
a) Electrical conductivity
b) Diffusion current
c) Refractive index
d) Absorbance
Answer: b) Diffusion current - The stationary phase in gas chromatography (GC) is:
a) Gas
b) Solid or liquid on solid support
c) Liquid
d) Mobile phase only
Answer: b) Solid or liquid on solid support - The principle of atomic absorption spectroscopy (AAS) is:
a) Emission of radiation by atoms
b) Absorption of specific wavelength by ground-state atoms
c) Fluorescence emission of molecules
d) Mass-to-charge detection
Answer: b) Absorption of specific wavelength by ground-state atoms - In NMR spectroscopy, the energy transition occurs due to:
a) Nuclear spin flipping in a magnetic field
b) Vibrational excitation of molecules
c) Rotation of molecules
d) Electronic excitation
Answer: a) Nuclear spin flipping in a magnetic field - Which of the following is a non-destructive technique?
a) UV spectroscopy
b) IR spectroscopy
c) NMR spectroscopy
d) All of the above
Answer: d) All of the above
