List of Drugs Used in Treatment of Orphan Diseases in Nepal
The 4th amendment of Drug Registration Regulation-2038 on 2078 includes the following 55 Drugs Used in Treatment of Orphan Diseases in Nepal.
List of Drugs Used in Treatment of Orphan Diseases in Nepal
| S.N. | Name of Medicine | Dosage form and Strength |
| 1. | Adrenocorticotropic Hormone | Powder for injection: 0.25 mg/vial |
| 2. | Vigabatrin | Tablet: 500 mg Powder for oral solution 500 mg/packet |
| 3. | Pyridoxine | Tablet: 25 mg (hydrochloride) |
| 4. | Immunoglobulins | Intramuscular administration: 16% protein solution Intravenous administration: 5%, 10% protein solution Subcutaneous administration: 15%, 16% protein solution Indicated for primary immune deficiency Indicated for primary immune deficiency and Kawasaki disease |
| 5. | Botulinum Toxins | Injectable powder for reconstitution 50 units/vial 100 units/vial 200 units/vial |
| 6. | Tetrabenazine | Tablet 12.5mg, 25 mg |
| 7. | Pyridoxal phosphate | Tablet 25, 50, 100, 250, 500 mg Extended release 200 mg Capsule 250 mg |
| 8. | Folinic acid | Tablets 5mg, 10mg, 15mg, 25mg Injection powder for reconstitution 50mg, 100mg, 200mg, 350 mg, 500mg Injectable solution 10mg/ml |
| 9. | Deferasirox | Tablet for oral suspension 125mg, 250mg, 500mg Oral tablet 90mg, 180mg, 360mg Oral granule 90mg, 180mg, 360mg |
| 10. | Deferoxamine | Powder for injection: 500 mg (mesilate) in vial |
| 11. | 6-Thioguanine | Tablet 40mg |
| 12. | Testosterone | Oral capsule 158 mg, 198 mg, 237 mg Injectable solution Cypionate 100mg/ml (Depo-Testosterone) 200mg/ml (Depo-Testosterone) Injectable solution Enanthate 50 mg/0.5ml 75 mg/0.5ml 100 mg/0.5ml 200 mg/ml |
| 13. | Dihydrotestosterone gel | 2.5% gel for topical application |
| 14. | Hydrocortisone | Powder for injection: 100 mg (as sodium succinate) in vial Tablet: 10mg, 20 mg |
| 15. | Growth hormone | Injection: 0.2mg, 0.4, 0.6 0.8, 1, 1.2, 1.4, 1.6, 1.8, 2 mg |
| 16. | Anakinra | Prefilled syringes 100mg/0.67ml |
| 17. | Tocilizumab | Injectable solution 20 mg/ml |
| 18. | Methotrexate | Powder for injection 1g/vial (25 mg/ml) |
| 19. | Methylphenidate | Oral tablets 5, 10, 20 mg |
| 20. | Atomoxetine | Oral capsule 5, 10, 18, 25, 40, 60, 80, 100 mg |
| 21. | Caffeine citrate | 10 mg/ml (each 1 ml solution contains 10 mg Caffeine citrate) |
| 22. | Prostaglandin | 5-10 nanogram/kg/min |
| 23. | Surfactants (beractant) | Intratracheal suspension 25 mg/ml |
| 24. | Concentrated RL | 3 mEq of sodium per ml |
| 25. | Semaglutide | Injection prefilled single dose pen 2 mg/1.5 ml ; delivers dose of 0.25 mg, 0.5 mg or 1 mg per injection |
| 26. | Testosterone Patch Gel | 2mg/24 hr 4mg/24 hr |
| 27. | Desmopressin nasal spray | 5 ml bottle with spray pump delivering 50 sprays of 10 mcg |
| 28. | Hydrocortisone | Oral tablet 5, 10, 20 mg |
| 29. | Fludrocortisone | 0.1 mg tablet |
| 30. | Testosterone | 100 mg/ml 200 mg/ml |
| 31. | Octreotide acetate | 1 ml single dose vials in 3 strengths containing 50, 100 or 500 mcg Octreotide |
| 32. | Pegvisomant | Powder for injection 10, 15, 20 mg 40 mg SC |
| 33. | Teriparaide | Prefilled injection pen 250 mcg/ml |
| 34. | Cabergoline | 0.5 mg tablets |
| 35. | Crizanlizumab | Injectable solution 10 mg/ml |
| 36. | Voxelotor | 500 mg tablets |
| 37. | Recombinant human thyrotropin | Powder for injection 1.1 mg/vial |
| 38. | Riluzole | 50 mg tablet Oral suspension 5 mg/ml (300 ml multidose bottle) |
| 39. | Pyridostigmine | Injection solution 5 mg/ml Tablet controlled release 180 mg Tablet 60 mg Syrup 60 mg/5 ml (250ml) |
| 40. | Interferon Beta | Prefilled IM syringe 30 mcg/0.5 ml Prefilled IM autoinjector pen 30 mcg/0.5ml Powder for injection 30 mcg/vial Prefilled SC syringes titration pack 8.8 mcg/0.2 ml (6 syringes) |
| 41. | Glatiramer acetate | Solution for injection 20 mg/ ml, 40 mg/ml |
| 42. | Intranasal triptans | 5 mg/ actuation 10 mg/actuation 20 mg/actuation |
| 43. | D-penicillamine | Tablet 250 mg Capsule 125 mg, 250 mg |
| 44. | Trientine | Capsule 250 mg |
| 45. | Antihemophilic factor VIII | 250 IU (Alphanate Humate P) 450 IU FVIII/450 VWF:RCo(Wilate) |
| 46. | Imiglucerase | Powder for injection 200 units 400 units |
| 47. | Anti Thymocyte Globulin | Injectable solution 50 mg/ml |
| 48. | FEIBA | Powder for reconstitution 500 units 1000 units 2500 units |
| 49. | Buprenorphine | Sublingual tablets 2 mg/8mg |
| 50. | Pomalidomide | Capsule 1 mg, 2mg, 3mg, 4mg |
| 51. | Ibrutinib | Capsule 70 mg, 140 mg Tablet 140 mg, 280 mg, 420 mg, 560 mg |
| 52. | Tolvaptan | Tablet 15 mg, 30 mg |
| 53. | Melatonin | 1-5 mg tablet |
| 54. | Pilocarpine | Tablet 5 mg, 7.5 mg |
| 55. | Panhematin | Lyophilized powder for injection 301 mg/vial 7mg/ml |
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