Timeline of Antibiotics

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Timeline of Antibiotics

This is the timeline of antimicrobial (anti-infective) therapy. The years show when a given drug was released onto the pharmaceutical market. This is not a timeline of the development of the antibiotics themselves.

  • 1911 – Arsphenamine a.k.a. Salvarsan
  • 1912 – Neosalvarsan
  • 1935 – Prontosil (an oral precursor to sulfanilamide), the first sulfonamide
  • 1936 – Sulfanilamide
  • 1938 – Sulfapyridine (M&B 693)
  • 1939 – Sulfacetamide
  • 1940 – Sulfamethizole
  • 1942 – Benzylpenicillin, the first penicillin
  • 1942 – Gramicidin S, the first peptide antibiotic
  • 1942 – Sulfadimidine
  • 1943 – Sulfamerazine
  • 1944 – Streptomycin, the first aminoglycoside
  • 1947 – Sulfadiazine
  • 1948 – Chlortetracycline, the first tetracycline
  • 1949 – Chloramphenicol, the first amphenicol
  • 1949 – Neomycin
  • 1950 – Oxytetracycline
  • 1950 – Penicillin G procaine
  • 1952 – Erythromycin, the first macrolide
  • 1954 – Benzathine penicillin
  • 1955 – Spiramycin
  • 1955 – Tetracycline
  • 1955 – Thiamphenicol
  • 1955 – Vancomycin, the first glycopeptide
  • 1956 – Phenoxymethylpenicillin
  • 1958 – Colistin, the first polymyxin
  • 1958 – Demeclocycline
  • 1959 – Virginiamycin
  • 1960 – Methicillin
  • 1960 – Metronidazole, the first nitroimidazole
  • 1961 – Ampicillin
  • 1961 – Spectinomycin
  • 1961 – Sulfamethoxazole
  • 1961 – Trimethoprim, the first dihydrofolate reductase inhibitor
  • 1962 – Cloxacillin
  • 1962 – Fusidic acid
  • 1963 – Fusafungine
  • 1963 – Lymecycline
  • 1964 – Gentamicin
  • 1964 – Cefalotin, the first cephalosporin
  • 1966 – Doxycycline
  • 1967 – Carbenicillin
  • 1967 – Rifampicin
  • 1967 – Nalidixic acid, the first quinolone
  • 1968 – Clindamycin, the second lincosamide
  • 1970 – Cefalexin
  • 1971 – Cefazolin
  • 1971 – Pivampicillin
  • 1971 – Tinidazole
  • 1972 – Amoxicillin
  • 1972 – Cefradine
  • 1972 – Minocycline
  • 1972 – Pristinamycin
  • 1973 – Fosfomycin
  • 1974 – Talampicillin
  • 1975 – Tobramycin
  • 1975 – Bacampicillin
  • 1975 – Ticarcillin
  • 1976 – Amikacin
  • 1977 – Azlocillin
  • 1977 – Cefadroxil
  • 1977 – Cefamandole
  • 1977 – Cefoxitin
  • 1977 – Cefuroxime
  • 1977 – Mezlocillin
  • 1977 – Pivmecillinam
  • 1979 – Cefaclor
  • 1980 – Cefmetazole
  • 1980 – Cefotaxime
  • 1980 – Piperacillin
  • 1981 – Co-amoxiclav (amoxicillin/clavulanic acid)
  • 1981 – Cefoperazone
  • 1981 – Cefotiam
  • 1981 – Cefsulodin
  • 1981 – Latamoxef
  • 1981 – Netilmicin
  • 1982 – Ceftriaxone
  • 1982 – Micronomicin
  • 1983 – Cefmenoxime
  • 1983 – Ceftazidime
  • 1983 – Ceftizoxime
  • 1983 – Norfloxacin
  • 1984 – Cefonicid
  • 1984 – Cefotetan
  • 1984 – Temocillin
  • 1985 – Cefpiramide
  • 1985 – Imipenem/cilastatin, the first carbapenem
  • 1985 – Ofloxacin
  • 1986 – Mupirocin
  • 1986 – Aztreonam
  • 1986 – Cefoperazone/sulbactam
  • 1986 – Co-ticarclav (ticarcillin/clavulanic acid)
  • 1987 – Ampicillin/sulbactam
  • 1987 – Cefixime
  • 1987 – Roxithromycin
  • 1987 – Sultamicillin
  • 1987 – Ciprofloxacin, the first 2nd-gen fluoroquinolone
  • 1987 – Rifaximin, the first ansamycin
  • 1988 – Azithromycin
  • 1988 – Flomoxef
  • 1988 – Isepamycin
  • 1988 – Midecamycin
  • 1988 – Rifapentine
  • 1988 – Teicoplanin
  • 1989 – Cefpodoxime
  • 1989 – Enrofloxacin
  • 1989 – Lomefloxacin
  • 1989 – Moxifloxacin
  • 1990 – Arbekacin
  • 1990 – Cefodizime
  • 1990 – Clarithromycin
  • 1991 – Cefdinir
  • 1992 – Cefetamet
  • 1992 – Cefpirome
  • 1992 – Cefprozil
  • 1992 – Ceftibuten
  • 1992 – Fleroxacin
  • 1992 – Loracarbef
  • 1992 – Piperacillin/tazobactam
  • 1992 – Rufloxacin
  • 1993 – Brodimoprim
  • 1993 – Dirithromycin
  • 1993 – Levofloxacin
  • 1993 – Nadifloxacin
  • 1993 – Panipenem/betamipron
  • 1993 – Sparfloxacin
  • 1994 – Cefepime
  • 1996 – Meropenem
  • 1999 – Quinupristin/dalfopristin
  • 2000 – Linezolid, the first oxazolidinone
  • 2001 – Telithromycin, the first ketolide
  • 2003 – Daptomycin
  • 2005 – Tigecycline, the first glycylcycline
  • 2005 – Doripenem
  • 2009 – Telavancin, the first Lipoglycopeptide
  • 2010 – Ceftaroline
  • 2011 – Fidaxomicin
  • 2012 – Bedaquiline
  • 2013 – Telavancin
  • 2014 – Tedizolid
  • 2014 – Dalbavancin
  • 2014 – Ceftolozane/tazobactam
  • 2015 – Ceftazidime/avibactam

Source :- https://en.wikipedia.org/wiki/Timeline_of_antibiotics

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