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Home Study Materials

Drug Induced Pigmentation Skin and Urine

Drug Induced Pigmentation Skin and Urine

Nabin Bista by Nabin Bista
May 9, 2021
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Drug Induced Pigmentation Skin and Urine
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Drug Induced Pigmentation Skin and Urine

Drug Induced Pigmentation Skin and Urine

Drug-induced pigmentation, or coloring, is a common side effect various drugs. It impacts many of the most commonly used medicines from tetracyclines and antimalarials, to NSAIDs and iron. Drug induces pigmentation topic is one of the frequently asked question in various types of exams i.e. Nepal Pharmacy Council License Exam and Pharmacy Loksewa.

Below, we’ve put together a comprehensive list of 20 drug-induced pigmentation effects that you need to know. You must know all these adverse effects, here we include syndrome like side effect of some drugs.

 

Drugs Side Effect
CimetidineBlue Urine 
PhenytoinDark brown skin patches

Purple glove syndrome

NitrofurantoinBrown Urine
Ethambutol Red green colour urine 
RifampicinRed/ Orange Colour Urine, Sweat & Tear
VancomycinRed man syndrome 
ClofazimineBrown pink colour pigmentation 
PhenazopyridineOrange urine
AmiodaroneBlue-gray skin discoloration
TetracyclinesDiscoloration / hypoplasia of tooth enamel
MinocyclineBlue-gray skin pigmentation
IronBlack stools
BismuthBlack tongue discoloration
LatanoprostPermanent iris discoloration
Heavy metal saltsSilver discoloration, gold discoloration etc.
ChlorpromazineBluish-gray skin pigmentation
ChloroquineBlue-gray skin pigmentation
NSAIDsFixed drug eruptions

Erythematous lesions that leave local

brown pigmentation. May occur on face,extremities or genitalia.

Cytotoxic drugsHyperpigmentation of skin

Diffuse pigmentation of nails



  • Important Drug Antidotes You Need to Know
  • Must Know Pharmacy Abbreviations
  • Adverse Drug Reaction (ADR)
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Nabin Bista

Nabin Bista

Hello, Thank You for visiting my blog I am Nabin Bista, Dedicated and self motivated young Pharmacist from Nepal. Blogging is my passion. I am studying B Pharmacy at Institute of Medicine - IOM. If you want me to write about any posts that you found confusing/difficult, please mention in the comments below.

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