• Privacy Policy
  • Terms and Conditions
  • Contact
Sunday, July 13, 2025
Pharma Info Nepal
  • Home
  • Vacancy
  • Courses
  • License
  • Loksewa
  • Questions
  • Downloads
  • Pharmacy Books
    • Pharmacy Act and Guidelines
    • Study Materials
  • Pharmacy Notes
    • B Pharmacy
    • D Pharmacy
No Result
View All Result
  • Home
  • Vacancy
  • Courses
  • License
  • Loksewa
  • Questions
  • Downloads
  • Pharmacy Books
    • Pharmacy Act and Guidelines
    • Study Materials
  • Pharmacy Notes
    • B Pharmacy
    • D Pharmacy
No Result
View All Result
Pharma Info Nepal
No Result
View All Result
Home Study Materials

Principles of Drug Action

Principles of Drug Action

Pharma Info Nepal by Pharma Info Nepal
May 22, 2021
in Study Materials
0
PRINCIPLES OF DRUG ACTION
2.2k
VIEWS
Share on FacebookShare on Twitter
ADVERTISEMENT

PRINCIPLES OF DRUG ACTION

Principles of Drug Action

Drugs (except those gene based) do not impart new functions to any system, organ or cell; they only alter the pace of ongoing activity. However, this alone can have profound medicinal as well as toxicological impact. The basic types of drug action can be broadly classed as:

1. Stimulation

It refers to selective enhancement of the level of activity of specialized cells, e.g. adrenaline stimulates heart, pilocarpine stimulates salivary glands. However, excessive stimulation is often followed by depression of that function, e.g. high dose of picrotoxin, a central nervous system (CNS) stimulant, produces convulsions followed by coma and respiratory depression.

2. Depression

It means selective diminution of activity of specialized cells, e.g. barbiturates depress CNS, quinidine depresses heart, omeprazole depresses gastric acid secretion. Certain drugs stimulate one type of cells but depress the other, e.g. acetylcholine stimulates intestinal smooth muscle but depresses SA node in heart. Thus, most drugs cannot be simply classed as stimulants or depressants.

3. Irritation

This connotes a nonselective, often noxious effect and is particularly applied to less specialized cells (epithelium, connective tissue). Strong irritation results in inflammation, corrosion, necrosis and morphological damage. This may result in diminution or loss of function.

4. Replacement

This refers to the use of natural metabolites, hormones or their congeners in deficiency states, e.g. levodopa in parkinsonism, insulin in diabetes mellitus, iron in anaemia.

5. Cytotoxic Action

Selective cytotoxic action on invading parasites or cancer cells, attenuating them without significantly affecting the host cells is utilized for cure/palliation of infections and neoplasms, e.g. penicillin, chloroquine, zidovudine, cyclophosphamide, etc. яндекс

Refrence: Essential of Medicial Pharmacology KD Tripathi 


  • Adverse Drug Reaction (ADR)
  • Drug Induced Pigmentation Skin and Urine
  • Don’t Use Some Drugs with Grapefruit
  • Important Drug Antidotes You Need to Kno

 

Tags: Study Materials
Previous Post

Nursing License Exam Questions Nepal Nursing Council

Next Post

The Pharmacy Store of Bharatpur Hospital is Running Against the Law

Pharma Info Nepal

Pharma Info Nepal

Pharma Info Nepal is the leading platform for pharmacy professionals, students, and healthcare workers in Nepal. We provide verified job updates, exam preparation resources (NPC & Loksewa), scholarships, and professional guidelines. Trusted by thousands, we also share timely updates from DDA, NPC, and MoHP to keep the pharmacy community informed and empowered. Join us to grow, learn, and lead in Nepal’s pharmacy sector. Thanks for visiting us | Pharma Info Nepal: Nepal’s No.1 Pharmacy Blog

Related Posts

Iodometry and Iodimetry: Principles, Differences, and Applications
Pharmacy Notes

Iodometry and Iodimetry: Principles, Differences, and Applications

June 6, 2025
Nepal Pharmacy Council Act 2057
Downloads

Nepal Pharmacy Council Act 2057

May 30, 2025
Pharmaceutical Calculations MCQs – 30 Questions with Answers
B Pharmacy

Pharmaceutical Calculations MCQs – 30 Questions with Answers

May 22, 2025
Understanding the Relationship Between BCS Classification and IVIVC
Pharmacy Notes

Understanding the Relationship Between BCS Classification and IVIVC: A Key to Smarter Drug Development

May 16, 2025
Medicines in the National Health Policy
Loksewa

Provisions Related to Medicines in the National Health Policy | Loksewa Frequently Asked Question

April 16, 2025
Understanding Types of Insulin: 30/70, 50/50, Lispro, Aspart, Regular & Glargine
Pharmacy Notes

Understanding Types of Insulin: 30/70, 50/50, Lispro, Aspart, Regular & Glargine

April 13, 2025
Load More
Next Post
The Pharmacy Store of Bharatpur Hospital is Running Against the Law

The Pharmacy Store of Bharatpur Hospital is Running Against the Law

Discussion about this post

Recommended

Nepal Pharmacy Council License Exam Model Question Set - 1

Nepal Pharmacy Council License Exam Model Question Set – 1

July 10, 2025
PHARMA JOB VACANCIES NEPAL

Vacancy Announcement Pharmacist and Pharmacy Assistant Nepal Army

July 10, 2025
M. Pharmacy Colleges in Nepal

M. Pharmacy Colleges in Nepal

July 8, 2025
Pharmacist Job Vacancy Nepal

Vacancy Announcement Magnus Pharma Pvt. Ltd QA, QC, and Production

July 1, 2025
List of CTEVT Constituent Colleges in Nepal

List of CTEVT Constituent Colleges in Nepal

June 29, 2025
  • Facebook
  • Twitter
  • LinkedIn
  • YouTube
  • Instagram

About Pharma Info Nepal

Pharma Info Nepal is a dedicated platform led by Nabin Bista, focused on empowering pharmacy students and professionals in Nepal. We provide high-quality educational resources, exam preparation materials, and professional guidance for pharmacy licensure exams and beyond. Our mission is to uplift the pharmacy profession in Nepal by fostering knowledge, skills, and excellence in pharmaceutical practice.

Explore our services, stay updated on pharmacy trends, and join a community striving for innovation and professionalism in healthcare.

Important Information

All content available on this website, including text, images, files, and other resources, is strictly protected under applicable copyright and intellectual property laws. Any reuse, reproduction, or redistribution of materials without prior written permission from Pharma Info Nepal is prohibited and may result in legal action.

Pharma Info Nepal operates as a registered company dedicated to maintaining the authenticity and integrity of its content and services.

Thank you for respecting our policies and supporting our mission to advance pharmacy education and practice.

Categories

  • B Pharmacy
  • Colleges
  • D Pharmacy
  • Downloads
  • License
  • Loksewa
  • M Pharmacy
  • Medicinal Chemistry
  • Notice
  • Nursing
  • Pharmacognosy
  • Pharmacology
  • Pharmacy Notes
  • Questions
  • Scholarship
  • Study Materials
  • Syllabus
  • Updates
  • Vacancy

DOWNLOADS

Pharmacy Book 

Pharmacy Act and Guidelines

About Pharma Info Nepal

About Admin

  • Home
  • Vacancy
  • Courses
  • License
  • Loksewa
  • Questions
  • Downloads
  • Pharmacy Books
  • Pharmacy Notes

© 2025 Pharma Info Nepal | All Rights Reserved

error:
No Result
View All Result
  • Courses
  • Questions
  • Downloads
  • About Pharma Info Nepal 

© 2025 Pharma Info Nepal | All Rights Reserved